University of Reading Research Data Archive

Dataset supporting paper ‘Acute effects of an anthocyanin-rich blackcurrant beverage on markers of cardiovascular disease risk in healthy adults: a randomized, double-blind, placebo-controlled, crossover trial’

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This dataset includes all summaries of raw data supporting the results presented in the paper "Acute effects of an anthocyanin-rich blackcurrant beverage on markers of cardiovascular disease risk in healthy adults: a randomized, double-blind, placebo-controlled, crossover trial". The objective of this paper is to investigate the postprandial effects of an anthocyanin-rich blackcurrant beverage (200 mL containing 711 mg anthocyanins) on a range of CVD risk markers in a healthy, middle-aged population. Data about CVD risk markers include: i. flow-mediated dilation (FMD) measured by Phillips CX50 integrated ultrasound system; ii. digital volume pulse (DVP) measured by PulseTrace PCA 2 device with finger photoplethysmography; iii. Blood pressure (BP) measured by by an automated sphygmomanometer; iv. platelet aggregation induced with two agonists: collagen (0.5 and 1 µg/mL final concentration) and ADP (10 and 100 µM final concentration) measured by chronolog optical platelet aggregometer; v. interleukin-8 (IL-8) concentrations measured by enhanced sensitivity cytometric bead array kit; vi. platelet-derived extracellular vesicles (PDEVs) and endothelium-derived extracellular vesicles (EDEVs) concentrations measured by flow cytometer. Data about plasma and urine anthocyanin and phenolic metabolites concentrations were measured by UPLC-MS/MS.

Resource Type: Dataset
Creators: Zhou, Ruihan
Contributors: Amini, Anna M
Rights-holders: University of Reading
Data Publisher: University of Reading
Publication Year: 2024
Data last accessed: 12 December 2024
DOI: https://doi.org/10.17864/1947.001321
Metadata Record URL: https://researchdata.reading.ac.uk/id/eprint/1321
Organisational units: Life Sciences > School of Chemistry, Food and Pharmacy
Life Sciences > School of Chemistry, Food and Pharmacy > Department of Food and Nutritional Sciences
Participating Organisations: University of Reading
Keywords: blackcurrant-derived anthocyanins, vascular function, cardiovascular disease
Rights:
Data Availability: OPEN

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