DriftScope (ver. 2.4; Waters) was used to extract the data, and msconvert utility from open source ProteoWizard software package (ver. 3.0.6893) was used to convert the data to mzML format. Open source pymzML (ver. 0.7.6) Python (ver. 3.4.) libraries were used to extract the data correspondingly. In-house developed scripts were used to analyse the data.