Anti-nociceptive effect of psilocybin in a preclinical model of neuropathic pain

1510 47 11005 11 53808 document 11005 Psilocybin_pain_2026_raw _data.xlsx application/vnd.openxmlformats-officedocument.spreadsheetml.sheet 4c8b5c8e29474f56269150b5d61a19bb MD5 34648 2026-03-26 14:05:32 https://researchdata.reading.ac.uk/1510/6/Psilocybin_pain_2026_raw%20_data.xlsx 1510 6 6 application/vnd.openxmlformats-officedocument.spreadsheetml.sheet spreadsheet en public cc_by_4

Psilocybin_pain_2026_raw _data.xlsx

data 2026-04-04 11010 13 53821 document 11010 Chronic_Pain_and_Psilocybin.docx application/vnd.openxmlformats-officedocument.wordprocessingml.document 7acb6e799f633831d0afe441e94af5b7 MD5 26090 2026-03-26 15:56:51 https://researchdata.reading.ac.uk/1510/9/Chronic_Pain_and_Psilocybin.docx 1510 9 9 application/vnd.openxmlformats-officedocument.wordprocessingml.document text en public cc_by_4

Chronic_Pain_and_Psilocybin.docx

readme 2026-04-04 11011 1 53824 document 11011 indexcodes.txt text/plain be2e70d04528efe2c21b85dda57df823 MD5 2163 2026-03-26 15:57:15 https://researchdata.reading.ac.uk/1510/10/indexcodes.txt 1510 10 10 text/plain Generate index codes conversion from text to indexcodes en public cc_by_4

indexcodes.txt

http://eprints.org/relation/isVersionOf https://researchdata.reading.ac.uk/id/document/11010 http://eprints.org/relation/isVolatileVersionOf https://researchdata.reading.ac.uk/id/document/11010 http://eprints.org/relation/isIndexCodesVersionOf https://researchdata.reading.ac.uk/id/document/11010 archive 8186 disk0/00/00/15/10 2026-03-26 15:57:46 2026-03-26 15:57:46 2026-03-26 15:57:46 data_collection show Maiarú Maria 922522 0000-0003-0927-6567 Pharmacy DataCollector Askey Tate 926716 DataCollector Allen-Ross Daniel 919500 CoInvestigator Stephens Gary 896772 Sponsor Gilmour Gary University of Reading lead Anti-nociceptive effect of psilocybin in a preclinical model of neuropathic pain 7_8592463f public pain psilocybin behavioural data This dataset contains behavioural data collected to investigate the anti‑nociceptive effects of psilocybin in a preclinical model of neuropathic pain in mice. The data were generated as part of research examining whether psilocybin can modulate sensory and pain‑related behaviours following nerve injury. The dataset includes results from a series of established behavioural assays designed to quantify different sensory modalities and motor function. Specifically, static mechanical sensitivity was assessed using the von Frey test, dynamic mechanical sensitivity was measured using the brush test, and cold sensitivity was evaluated using a thermal preference place test. In addition, locomotor performance and general motor coordination were examined using the rotarod test. Together, these datasets provide a comprehensive behavioural profile relevant to sensory processing, nociception, and motor function in the context of psilocybin administration. 2026 published University of Reading 10.17864/1947.001510 Academy of Medical Sciences https://doi.org/10.13039/501100000691 SBF008\1092 Compass Pathfinder Ltd Investigating the analgesic properties of psilocybin in preclinical models of chronic pain Dataset University of Reading en en 2026 researchdata@reading.ac.uk AdminContact yes TRUE Creative Commons Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Creative Commons Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ TRUE Title: Psilocybin ameliorates neuropathic pain-like behaviour in mice and facilitates gabapentin-mediated analgesia Authors: Tatum Askey†1, Daniel Allen-Ross†1, Daniil Luzyanin1, Reena Lasrado2, Gary Gilmour2, Stephen P Hunt3, Francesco Tamagnini1, Maqsood Ahmed2, Gary J Stephens1, Maria Maiarú1* Status: in press open TRUE